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Marie-Anne Shaw, University of Leeds, UK

Marie-Anne Shaw is a geneticist with a long standing interest in human genetic susceptibility to infectious disease. Her BSc, PhD and first postdoctoral research focussed on aspects of human genetics and immunology, all based at University College London. On joining Jennie Blackwell’s group, first at the London School of Hygiene and Tropical Medicine and then at the University of Cambridge, she started to apply rapidly developing analytical approaches to investigate susceptibility to complex disease caused by intracellular macrophage pathogens. In the mid nineties Marie-Anne started her own group at the University of Leeds and expanded the range of diseases, now including cutaneous leishmaniasis, tuberculosis, malaria and helminth infections. Many of the projects have necessitated de novo sampling at enjoyable field sites worldwide. Analysis is appropriate to multifactorial disorders, first establishing heritability, followed by gene identification. Since being at Leeds she has divided her time between infectious diseases in humans and domestic species, and genetics associated with adverse drug reactions, in particular inhalation anaesthetics. She is a founding co-editor of Infection, Genetics and Evolution.

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